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Histoplasmosis in a Cat
History: 2-year-old cat, domestic short hair, intact female, having a history of sneezing and unilateral purulent nasal discharge. No foreign body was found on rhinoscopy. Nasal swabs were submitted Cytological description: The images show numerous macrophages, small and medium-sized lymphocytes, lymphoblasts, and neutrophils with scattered young spindle-shaped cells and epithelial cells. There are multiple round to oval structures, 2-5 microns in diameter, showing a pale blue cytoplasm and an eccentrically placed crescent-shaped purple nucleus. These are found between and within the macrophages. The structures' morphology is compatible with Histoplasma capsulatum. Comments: Histoplasma organisms may be found in many organs. The lung, bone marrow, liver, spleen, and lymph nodes are most frequently affected.
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